If a woman doesn't come or have an orgasm, can her ovaries hurt just like a man's testicles can hurt if he doesn't come?

Since orgasms cause a release of endorphins into one's cerebral-spinal fluid and endorphins are also somewhat responsible for the emotion of happiness, etc., is it possible that excessive masturbation and/or intercourse would lead to a depleted level of endorphins in the system that could in turn cause one's affect to become somewhat "flat"? Could a sustained low level of endorphins in the system induce depression and/or mood disorder?

Hi! I have a question about orgasms. I'm a female who has masturbated since her early teens and wonder if I've "overdone" it somewhat. I did it so frequently (sometimes every other day or so; sometimes I waited longer) that now that I'm in my early 20s, I find it harder to reach orgasm, and harder to have multiple orgasms (it used to come so easily to me). Have I "lost" that momentum? Can I regain it if, say, I stopped masturbating for several weeks or months?

Also, my partner stimulates me manually or with his tongue, and I haven't been able to "come" yet... is it because I've masturbated too much? Do women take longer to come? I think he gets bored doing it...