I recently went to my doctor because I've been unable to lose weight. I've been on a successful diet, accompanied with a reasonable exercise plan, but I've seen no real results. A series of tests were run — I've got optimum blood pressure, low cholesterol, and I am not diabetic. But, when my cortisol levels were checked — they were very high. The doctor suspected there was a possibility that I might have Cushings' Syndrome — but another test was run and that came up negative.

I was doing research on the internet, and I found that there was a link between excessive cortisol and depression. I was diagnosed with clinical depression when I was 12 (I am now 21). And I am currently untreated. What is the link between cortisol levels and depression? Are excessive cortisol levels a physical manifestation of depression? Or does an excess of cortisol for some other reason cause depression? Does an excessive amount of cortisol cause weight gain, or in my case prohibit weight loss? And if there is a connection — will treatment for my clinical depression (in the form of prescription pills) help me?

I've been unable to find answers anywhere, or at least a good source to tell me to stop worrying — any help would be appreciated.

I compete in an individual sport. The problem is that on the day of a major competition, I have really bad indigestion. Sometimes, I have to run to the bathroom every half hour for a bowel movement! Besides being annoying, disgusting, and a little embarrassing, this interrupts my competition and adds unneeded stress. Why is this happening and what can I do to prevent it?

1) I think I might have OCD. I worry about it a lot and I want to go to a doctor, but I am too afraid. Can you please tell me the symptoms of OCD. Thank you.

2) I think I might have OCD. Since I was about 12 or 13, I started thinking really strange thoughts. I always felt like there were eyes watching me. I know its irrational to think such a thing, and I know there aren't any, but I get this weird feeling there are. I have to cover my windows in dark colored papers and check for any holes in them regularly, so there isn't the tiniest hole for someone to peek through. I have shades as well, but I never feel like they're enough. I also have to regularly make sure my windows are locked, sometimes I'll lock and relock them a couple times until it feels like the lock worked. The same with my bedroom door, I will not sleep at night if my door is unlocked, and sometimes I relock it more than once, or even reclose my door more than once. It doesn't always feel like it properly shut the first time. I also have to turn any faces away from me. My stuffed animals can't look in my direction, and I wont hang pictures up in my room if it feels like it has eyes on it. I'm not scared of eyes necessarily, I know some people with beautiful eyes. I just can't take them staring at me. I also know they wont hurt me, either, but it feels as if somehow they will. I don't know how.

I'm really feeling like I might be going crazy. I'm stressed out beyond belief! Should I bring it up with my doctor? Should I get a therapist? Could this be OCD?

Whenever I am physically intimate with a girl or even if I suspect eminent intimacy, I begin to tremble uncontrollably. This makes me feel quite awkward and self-conscious. Also this is the only time it happens. Is this a treatable disorder? Is there perhaps some sort of quick fix solution such as getting slightly inebriated before such an encounter?

I think I just had my breaking point. I don't know how much more stress I can take. I tried to check out stress-reduction workshops, but the next one is next semester. I don't really want to see a psychiatrist. I don't know what to do. Basically, I think a lot of my stress is because it is just so difficult for me to focus or concentrate on anything. My thoughts are running everywhere. I try, I really do. I even moved into a single for it. I feel so incompetent. I don't give a damn about making friends. I'm always feeling lonely. And worst of all, there is always something that makes me so worried, panicked, to the point of just wanting to die to relieve me of it. I have chest pains when I sleep sometimes. Whenever I do anything away from my desk during my designated "study time," I feel so guilty. Since transferring here this semester, I have never felt confident, relaxed, or satisfied about anything. Everything annoys me. I annoy me. This letter probably sounds really unorganized, but I can't organize my thoughts. I went to see a Broadway play and loved it, but just really hated myself for seeing it when there was so much work I had to do. I've decided I don't want to live like this anymore. I'm tired of not being able to breathe and get chest pains when I get stressed. Please help me.

What can you tell me about test-taking and mental block issues?

I am a graduate student, doing very well in my coursework and research. However, I feel extreme anxiety in doing anything, e.g., starting a problem set, writing a program, etc. I wonder, what are the common causes of anxiety and what I may be suffering from. I would like to be calm and relaxed and not anxious and stressed. I know about meditations, etc., but what I would really like is some psychological insight.