1) I have a large amount of course work, which is combined with a job and extra-curriculars, and while I want to succeed in all of them, I find that I simply don't have enough time, even though I currently sleep only 4 or 5 hours a night. I mentioned this to a group of my friends here at school, and it turns out they all take stimulants to help them manage jam-packed undergraduate life. The pills are called ADDERALL and PROVIGIL. I have acquired some for myself, but before I take them, could you tell me if either has serious health risks? I do not have any other health problems or take any other medications. A few of my friends tell me that they sometimes stay awake for as long as 3 or 4 days. If it is reasonably safe, that would be great! Thank you.

2) Given the fact that this is a top-notch school, it's total hoo-ha that you haven't included any info on all the non-hard core, but still illegal, "study stimulants." Is all this ADDERALL gonna do me permanent damage or what?

My question is this, How much do you know about what the asthma medication called Clenbuteral does to a normal healthy male in regards to body building? What are the adverse effects? And I don't need to be preached to about why I should take it or not. I just want the basic gist of what it does. Can you answer this? By the way this drug is not used in the US for any reason.

I have a history of "experimentation" (infrequent or occasional use of ecstasy, 'shrooms, and other drugs — mostly prescription pills). I am completely sober now, but am worried about long-term damage to my brain. I used drugs infrequently (no more than three to five times for each substance), but drank regularly. How worried should I be? Is there anything I can do to combat long-term effects?

Is it true that women can apply testosterone cream to their vaginal area to increase sex drive?

1) I have two friends who I think are drinking too much. I don't know what to do. They are very defensive should anyone say anything to them about their excessive habit, and a lot of our friends are giving up on them. This has become a daily thing and their schoolwork and friendships are all suffering. They are both 21; one recently broke up with his girlfriend of several years and the other has been single for a while and he hates it. I know that has a lot to do with it. Please suggest some non-intrusive ways to help them. I'm really at a loss.

2) Last year, I became very good friends with a guy on my floor. He was a little out of the ordinary in the way he dressed, as well as in some of his opinions and habits. I had the feeling that he did drink more than he should, and he also did pot. I did not worry too much about it because it appeared to be more of a lifestyle choice than an addiction, and it did not cause him major troubles.

Unfortunately, he started to have academic problems. He did not do his work, missed classes, and eventually exams as well. I still did not relate these things to his alcohol and drug habits, and I hoped that once he got over the adjustment everyone needed to make in freshman year, he would be fine. Well, he wasn't. He did not come back to school this fall, and when I called him, I learned that he had gone through a lot that summer. He was diagnosed with depression and a cocaine addiction, put on Prozac, and sent to therapy. At that point, I thought that he was on the right track because he was also going to get a job and planning to take classes at a nearby college.

However, when he came to visit me a month later, he had already had two beers before he even came here and got more and more drunk as the evening progressed. I would not let him drive home, but he ignored my warnings and left anyway. I was very disturbed because a friend of his had just been in a drunk driving accident. I was very mad at him, told him clearly that I will always be his friend but prefer not to talk to him or see him if he showed up drunk again. He did not call for a while and neither did I. When he called me yesterday and I told him that I thought he should do something about his alcohol problem, he kept repeating his excuses, that he drinks because he is Irish, that he doesn't care if he dies early as long as he had fun in life, etc. On the other hand, he can't find a job and seems to be very depressed. I want to help him, but I don't know how. Any ideas?

1) What are the long-term and short-term effects of abusing NyQuil? I've heard it's very dangerous to use it recreationally, but I'm not sure what's dangerous about it. I've heard you can even die from abusing it.

2) I have recently just finished my first year in college and on a few occasions, a couple of friends and I had decided to drink massive amounts of Robitussin DM (dextromethorphan, I believe). It was fun, but the day after I felt like I was hit by a car! They call it robo trippin'. I have no intentions on doing this again; however, I was wondering if there were any long-term effects of it.

I like to use codeine occaisionally (once or twice a week at most) to help me relax and feel a minor high. Typically, I'll take about 90 to 150mg per session (100 to 200mg per week on average). Sometimes I take Tylenol-3's, and sometimes I extract the codeine from these pills and drink it pure. What are the potential health side-effects of this usage, both short- and long-term?

Thanks!

I am a freshman on a collegiate varsity sports team. Team gatherings, when we are not practicing, usually consist of excessive drinking with and without drinking games. I did not drink in high school and when I tried drinking with the team it made me feel really sick. I want to bond with my teammates (they are really great when not drunk) but I don't know how because if I am the only guy in the room not drinking I can't play drinking games with them, discuss favorite types of alcohol, or even carry on a real conversation because at a certain point in the night they stop forming coherent sentences. I need to be friends with this group of people but I would like to do so in a way that allows me to remember the night in the morning. Is this possible? What should I do?

While I don't really approve of their lifestyle (why devote six days a week to practice only to reduce your performance with alcohol?), I make no moral judgement. I don't want to change their way of doing things, I just want them to respect my way.

I only smoke occasionally. I smoke when I go out to clubs, etc. (once or twice a week). I smoke about ten cigarettes each time. Is this likely to have an impact on my health?

Hi! Your site is very helpful. I have a few friends who smoke. We are friends since the past four years; they started smoking about a year ago. They tell me to smoke, I don't do it, so they call me a jerk. I have never TOUCHED a cigarette in my life.

Should I smoke?

If I smoke one cigarette about once a week, will it harm me in any way?

Will it make me a chain smoker?

Which is the safest brand of cigarette, health wise?

I think it would be a good idea for me to stop smoking marijuana and cut down on my drinking, at least during the school year. The problem is, I have been doing it for so long it is almost as though I have forgotten how to have fun without it. Contributing to this problem is the fact that many of my friends smoke or drink to have fun. Many of my other friends just do not seem to have fun at all; they stay in Friday and Saturday nights to do work. I've found it difficult to quit, I think because I'm just not sure of what's out there to do that's fun without being stoned or drunk. Can you recommend anything that's fun whether you're intoxicated or sober, so that I don't have to stop hanging out with certain friends if I want to relax and have fun? I want to finally enjoy life without relying on an altered state of consciousness. What's there to do when you're sick of renting movies? Also, any tips for resisting the urge to take people up on their offer to toke up? (I'm never pressured into it, but it's like the dieter who's offered some chocolate cake — it's there, it looks sooo good, and the fact that other people are doing it makes it seem more "okay.") Thanks so much.

I am a 32-year-old woman dating a very nice man my age. My boyfriend and I have been dating for just about a year and we are serious about each other. He has severe asthma and has to be on high doses of steroids during and for a long time after a flare-up. The problem is these steroids have a terrible effect on him: he breaks out in acne; he is irritable and loses control of his temper; his appetite is voracious; he puffs out in his stomach and face.

The problem with his temper and irritability is what most bothers me, it is as if he has a completely different personality and sometimes it is frightening. We have talked to his doctor who says that these steroids are the drug of choice and if he does not take them as an outpatient, he would have to be hospitalized and put on the same medications.

As I said, his personality can be frightening on the steroids, but I have seen my boyfriend in an asthma attack which is even more frightening. I once talked to a therapist about this problem. Maybe I should have been more careful in choosing a therapist, but this woman came from a feminist perspective and in a sense told me that I should break up with this man. I don't think that this is the solution since I love him very much and I know that off steroids he is the man I love.

Could you possibly tell me the interactive effects of Zoloft (the anti-depressant) and MDMA (Ecstasy)?

I am a teenage girl currently taking Adderall (20 mg) to treat my ADHD. My question: does taking this medication affect sexual wantings or behavior? I am supposed to start taking it at 7:00am so it will wear out at about 9:00 or 9:30pm. Since I go out later at night, my medicine is usually worn off before I engage in any kind of sexual activity. But sometimes on weekends I wake up late and have to take it at later times such as 12:00 or 1:00pm. Since then it will not wear off until after I go out, would being on Adderall affect my sexual behavior? I feel like I am less "horny" when on Adderall and sex is worse because of the lack of my desires. Does this have anything to do with my medicine or is it just a coincidence?

I originally took a muscle relaxer because I was experiencing very bad back pain and could not sleep. I was not prescribed the muscle relaxers. My friend suggested I take one of hers. So I did, and now I will take one sometimes before bed if I can't fall asleep or if I want to actually just relax. It makes me just want to sleep, and I feel really calm after taking one. Is this bad that I take them for this reason? What are the side effects? Is it harmful?

I have been taking between 5 and 10 mgs of methadone daily. I cannot seem to stop. Every time I try, I get very, very depressed and experience abdominal pain, chills, hot flashes, and sleeplessness. The depression and tremendous anxiety are intolerable and I end up taking more to avoid it. Question: Am I harming my body and/or mind with this stuff? How can I get off without the horrible feelings?

My friend and I snorted a 10 bag each of heroin. Our heads began to feel heavy after ten minutes. Soon we entered into a dream world in which we hallucinated heavily. We talked to people who did not exist and we were very confused. I could not remember anything about who I was. I only remember certain parts of the four-hour trip that followed but I felt like I was on mushrooms for about two days. We could not read for that amount of time (nothing was in focus). What do you think we took? PCP? Bad synthetic heroin?

Recently I have started snorting Ritalin and Adderall (not at the same time though). I have found that the effects closely resemble that of snorting cocaine, but are not quite as intense. I really like doing this, because it's much cheaper than buying coke. However, I was wondering exactly how dangerous this might be, if even at all, considering it's a prescribed drug and I never snort more than the average dose that you would take orally. If you could tell me what the danger in doing this is and what I might possibly be doing to my body, that would be great.

I'm thinking about trying heroin. However, this prospect makes me nervous because of all the media reports of people becoming so quickly addicted to it, wasting away, and even dying from overdoses. Any advice?

I know that it is extremely dangerous to mix viagra (or other ED drugs) and poppers (amyl nitrate), and that one should wait for 24 hours after using viagra (to let it get out of your system) before using poppers. My question is what is the waiting period after using poppers before it is safe to use viagra? In other words, how long before the physiological effects of poppers wear off?

A couple of questions for you: what are the long-term side effects of one abusing prescription painkillers, such as Vicodin? What advice can you give to someone who has gotten off of them to help them stay off???

I have been shooting cocaine steadily for almost two months now and want to know what the difference between the physical and emotional addiction is. I am not sure if I have been experiencing withdrawals, but I feel sick a lot lately. I know shooting heroin has made me sick before. Can cocaine eventually make you dope sick as well?