Since orgasms cause a release of endorphins into one's cerebral-spinal fluid and endorphins are also somewhat responsible for the emotion of happiness, etc., is it possible that excessive masturbation and/or intercourse would lead to a depleted level of endorphins in the system that could in turn cause one's affect to become somewhat "flat"? Could a sustained low level of endorphins in the system induce depression and/or mood disorder?

I was wondering about the depth of the vagina. I've read statistics that say that the average vagina is only 3 to 4 inches deep. This seems way too small to me, since the average penis is considerably longer than that. Wouldn't that mean that most penises would crash into the cervix repeatedly during intercourse? Since this obviously doesn't happen, my question is this: does the vagina actually elongate during intercourse to accommodate the entire length of the average penis?

Dear Alice, 

I take Valtrex daily to protect me from cold sores I get on my face. I haven’t had one since I started taking it a few years ago. My partner gets cold sores on his mouth and has recently performed oral sex on me while having a cold sore. Will the daily Valtrex protect me from developing genital herpes? How will this affect me in the future?

Hi! I have a question about orgasms. I'm a female who has masturbated since her early teens and wonder if I've "overdone" it somewhat. I did it so frequently (sometimes every other day or so; sometimes I waited longer) that now that I'm in my early 20s, I find it harder to reach orgasm, and harder to have multiple orgasms (it used to come so easily to me). Have I "lost" that momentum? Can I regain it if, say, I stopped masturbating for several weeks or months?

Also, my partner stimulates me manually or with his tongue, and I haven't been able to "come" yet... is it because I've masturbated too much? Do women take longer to come? I think he gets bored doing it...

What are the risks of HIV infection for the passive partner of oral sex?

My wife and I had our first child last July. Until about 3 months ago, she was unable to reach orgasm at all. Of late, she has very small one's, but they don't seem to be getting much better. Prior to having the baby, she had strong, very quick (3-5 minutes) orgasms 90% of the time. I know the stress of being at work rather than home with the baby could play a part in this. Is this common and is there a way to mitigate the problem? 

If one has a long-term partner and neither AIDS nor any other STD is a concern, is there any medical reason not to perform cunnilingus on a menstruating woman? My significant other is particularly horny during her period and would love cunnilingus at this time. I am willing but curious.

I am curious about double penetration (two penises in one vagina). Because of the increased friction, even if both men are wearing condoms, is there more of a risk that the condoms would break?

I currently use NuvaRing for contraception. Because the ring slowly emits hormones into the body via the vagina, my partner and I are wondering whether he will have an unhealthy amount of contact with these hormones during oral sex. Thanks.

I am a well-adjusted late twenties male with a steady girlfriend. Lately, I have been increasingly fantasizing about various types of anal penetration. I have discovered that during masturbation, this brings me very intense pain/pleasure. Even though I think it may be satisfying to experiment with a vibrator or other objects inserted by my girlfriend, I find myself drawn toward trying the real thing (i.e., having anal sex with a penis). The problem is, I definitely do not consider myself homosexual and, in fact, the thought of the actual act with another man actually repulses me. Am I trying to have the real thing without going through a bisexual experiment or what?