I've thought and thought about this, but can loneliness kill you? I've lived through my teenage years, twenties, three-quarters of my thirties, but am still hoping that just around the corner will be the one. If not — can loneliness kill you?

Can Reye's syndrome cause chemical imbalances later in life? My mother had it as a teenager and has really bad mood swings and possible hypochondria and my aunt and I are trying to figure out if having Reye's syndrome could be the cause for some of it.

1) This is more of a coping question. I am a first-year who applied for a single room over the summer and was denied. I figured that everything would be okay nevertheless. I tried to look at the situation as a character-builder. Well, that is not the case. My roommate is very depressed. I talked to the RA on my floor, but she didn't take any action, except to talk with her. Unfortunately, my roommate is so ashamed of what's happening that she denied the facts, and the RA believed her. No one except me has realized yet that she is sleeping most of the day and all of the night, and that it is indeed a real problem. I have expressed my concern to her and encouraged her to go to counseling services. She went a couple of times and then started canceling appointments left and right. I have worried about her, but I have no backup whatsoever, so there is really nothing I can do to help at this point. We get along relatively well otherwise.

Right now, the concern I have is that her depression is pulling me down, too. I literally have not been alone anywhere for more than two to three minutes in weeks. I wanted a single because it's a requirement that I spend some time by myself, and I'm going crazy these days. The lights are always out in the room, and I've noticed that I'm sleeping more than usual myself as the situation has progressed. Also, I am having to deal with some personal issues of my own this semester, and I simply don't have the energy to take care of someone else who desperately wishes that I would do so. Any ideas would be greatly appreciated.

2) I know that when a friend is depressed, it's important to reach out, discuss the issue, and be there for the person as much as possible. But that's quite hard to do when I myself have a history with depression — I feel as if her emotions are taking me back to a place that I don't want to go. I really empathize with my friend and feel her pain, but at the same time know that I'd be useless to both of us if I'm in the troughs too. How can I help without sacrificing my always precarious emotional equilibrium?

I'm the peacemaker among my friends, the introverted listener. But lately I find myself dealing with my friends and their problems more than ever. The problems drift from abuse in their homes, relationship problems, suicide, and MORE! It seems like I'm walking around with the weight of the world on my shoulders — literally, and its making me dive headfirst into depression. Don't get me wrong, I like being trusted and thought wise for advice I give, but sometimes I know I'm just being used, and all I need to do is listen. But I also feel helpless towards many of the situations, example, drug abuse or violence in their homes. They're expecting my help most of the time! I can't suggest counselors, because it's un-thought of here, my friends usually have been to more than their fair share in their years, and it flat out doesn't work. Our school counselors are bogus, teachers really don't listen, and I'm a small girl who can't necessarily take on the world!! On top of trying to help friends of mine (close and not-to-close) I've got my own problems too! It's insane.

A loved one of mine had a double mastectomy due to a rapid growing breast cancer, chemotherapy, and radiation. She is in her early 30s. She is a year out from treatment/surgery and suffers daily with aches and pains. She also has lymphedema in her right arm, which doesn't help with her discomfort. She feels pain in her joints, sometimes her back, she gets headaches, she is often fatigued, and she feels sick a lot. She's forgotten what it feels like to have her body feel good. Is this normal? She definitely has depression due to this and often thinks she will get cancer back somewhere else. It's been two years since her diagnosis and she has not felt a day of no pain and or sickness. I want to give her some good feedback, some light at the end of the tunnel so to speak (without using that phrase) to help her get through it. The doctors aren't too helpful. Mostly they want her to take more pills, which are becoming the size of a meal. She refuses to take the pills that are anti hormonal. I don't blame her; she can't handle the menopausal symptoms they give her on top of everything else. She is active and often just pretends to feel ok for others sake. She also eats well with a low salt diet to help the fluid in her arm. Should there, or will there be relief after undergoing so much stress on ones body?

I am a New Yorker who is in college at the moment. Several of my friends from school are living and working in the city this summer, and I love having them around. Whenever I make plans with them, though, I feel a great pressure to make sure they have a good time. As the person who knows New York best (the subway, good restaurants, etc.), I feel like it is my responsibility to make plans and decisions when we go out, and I feel inordinately guilty or embarrassed if the plans ever go awry (e.g., if I mistake the address of a bar, if a restaurant turns out to be unexpectedly expensive, or even if the local subway line unexpectedly switches to the express — things that are often totally out of my control). I know this is silly; my friends can clearly take care of themselves, and I know they don't depend on me for fun. But the pressure that I create for myself is detracting from my own enjoyment. How can I stop holding myself to these absurd expectations and just enjoy myself?

I'm currently coming into my second year at a famous but huge university in a big, crowded city. My first year had its ups and downs, but I made a couple friends. The problem is, I commute, and I'm finding it hard socially. I've been depressed for the past year, thinking I'm regressing because I'm not meeting as many people as a normal student would. How does one go from meeting someone in class to hanging out with them on weekends? I feel like I am mostly the one initiating, so I feel like I'm imposing. In addition, the university is rigorous, so I don't always have the time to join the clubs. Any tips on how to make a lot of friends from classes even though I am not dorming?

I am a freshman who has just moved into the "social dorm." It's only been a few days, but I already feel like my place in the social strata is being cemented — I'm somewhat overweight, and although I can be very talkative and can force myself to make the effort to meet people despite being nervous, I feel like I'm already being classed as one of the straight-edge less popular types. I don't mind that I'm not the type who makes 500 friends instantly; I'm still managing to make a few good acquaintances/potential friends.

The problem is that the people I make friends with aren't really the party types, and while I'm not a huge party person either, I still want to get to go to some and have the whole "college experience." How is it that other people are "in the know" about parties and stuff like, as soon as they get here? What are the qualities that make them seem to bond so instantly? How do I get myself invited to at least some of these events?? I don't want to crash the parties and show up alone...

Recently, I've noticed that my one or two of my friends have taken to cutting themselves. I'm concerned for them... but I've done the same thing in the past and they know it. How do I confront them without sounding like a hypocrite?

Your advice to "Surround yourself with positive, healthy people" is good. But this is part of my insecurities. It seems that everyone will want to surround themselves with positive, healthy people; but if I'm not healthy mentally, why should people want to be around me? I fear I'm excluded because, even when I try to hide my insecurities, they still show and people don't want to be around a "downer." Any advice on this aspect?

My best friend and I got into a fight. It's been a month and he won't speak to me. He says that he needs time, but that's the one thing I can't give him. I feel so hopeless and I've gone back to cutting after being clean for 11 months. I'm just so sad all the time and it just hurts — so much more than I know how to describe. And I know I shouldn't allow my happiness to be dependent on another person, but it is because he was the only one that actually cared. And I just don't know what to do. I can't bring myself to go to see psychological services and I tried calling hotlines, but I just can't go through with it. I'm trying to move on, but I just want the pain to stop. I miss him so much. And I apologized profusely, but he doesn't care. He doesn't care and I can't handle it. I'm just so upset and I just need help. I don't know what to do.

I am a 22-year-old male grad student, now starting my second semester at in graduate school. I have been doing very well academically, but my studies and my work-study job leave me absolutely no time for a social life! I have not been on a date since I got here; though I meet a lot of interesting people, and am in the habit of collecting their phone numbers. However, I can never seem to find any time to spend with them. Sometimes this really depresses me. I have noticed that I have lately been smoking much more heavily than I used to.

I was adopted when I was two and a half years old, and I still have a lot of issues from it. I don't really like myself and at times; I feel like I don't know who I am. I never let myself become close to my adoptive family, and still feel uncomfortable and out of place around them. I don't have many friends. I isolate a lot and don't really trust people. I am always scared to make friends for fear that I won’t be accepted or liked. Growing up I often turned to drugs and alcohol to escape these feelings and to feel comfortable with myself. The problem now is that I am 22 and I have a two year old daughter. I feel like I need to get over this so I can be a good mother to her, and raise her to know and love herself. I feel lost, what can I do?