1) I have two friends who I think are drinking too much. I don't know what to do. They are very defensive should anyone say anything to them about their excessive habit, and a lot of our friends are giving up on them. This has become a daily thing and their schoolwork and friendships are all suffering. They are both 21; one recently broke up with his girlfriend of several years and the other has been single for a while and he hates it. I know that has a lot to do with it. Please suggest some non-intrusive ways to help them. I'm really at a loss.

2) Last year, I became very good friends with a guy on my floor. He was a little out of the ordinary in the way he dressed, as well as in some of his opinions and habits. I had the feeling that he did drink more than he should, and he also did pot. I did not worry too much about it because it appeared to be more of a lifestyle choice than an addiction, and it did not cause him major troubles.

Unfortunately, he started to have academic problems. He did not do his work, missed classes, and eventually exams as well. I still did not relate these things to his alcohol and drug habits, and I hoped that once he got over the adjustment everyone needed to make in freshman year, he would be fine. Well, he wasn't. He did not come back to school this fall, and when I called him, I learned that he had gone through a lot that summer. He was diagnosed with depression and a cocaine addiction, put on Prozac, and sent to therapy. At that point, I thought that he was on the right track because he was also going to get a job and planning to take classes at a nearby college.

However, when he came to visit me a month later, he had already had two beers before he even came here and got more and more drunk as the evening progressed. I would not let him drive home, but he ignored my warnings and left anyway. I was very disturbed because a friend of his had just been in a drunk driving accident. I was very mad at him, told him clearly that I will always be his friend but prefer not to talk to him or see him if he showed up drunk again. He did not call for a while and neither did I. When he called me yesterday and I told him that I thought he should do something about his alcohol problem, he kept repeating his excuses, that he drinks because he is Irish, that he doesn't care if he dies early as long as he had fun in life, etc. On the other hand, he can't find a job and seems to be very depressed. I want to help him, but I don't know how. Any ideas?

I have been doing weed for about six months now and on occasion a few other drugs. I usually do it only on average three times a week and a lot more on the weekends. I feel that it is ruining my life because my concentration is terrible and my marks have dropped significantly (20 points). I feel like I'm in a dream all the time and it just isn't fun anymore. I have heard that pot is not addictive but I have tried to stop but I feel sick and irritable if I don't smoke up. I have realized I need to quit but I can't. Why can't I stop if this "soft drug" is not addictive? Am I crazy? Please help. I want my life back. Thank you so much.

I have never had a problem with alcohol tolerances in the past. I could drink at least four or five drinks and be fine that night and the next morning. Now, I find myself getting violently sick after drinking just one or two. Even after a glass of wine I want to puke it up. Is there something physically wrong with me? I know the obvious solution is to stop drinking entirely. But, I shouldn't be this sick after drinking just one drink. Have you ever heard of this before? Can you help me figure out the problem?

My granddad has been an alcoholic for ages — way before I was born. I am really worried about my granddad’s drinking. My father doesn't like me to see him when he is drunk, but that is kind of hard. What are the best groups for alcoholics? And most importantly, what should I do?

My uncle shoots heroin. My father used to do cocaine. My moms' (both of them) used to smoke weed with their friends when I was eight. I smoked weed when I was twelve. I sold weed at 14.

I don't want to continue in the vein of my addictive family (no pun intended). How hereditary is addiction? What measures can I take to avoid falling into the same hazy trap of my family members?

On "big nights out" (about once a month) friends of mine "plug" ecstasy tablets — by which I mean they each stick one up their butt instead of swallowing.

They claim that is a "safer" way to ingest E because it bypasses the liver and goes right into the bloodstream. They also claim the effects are heightened.

I have been tempted to try this method as they swear by it, but thought I'd get your opinion first — are there any potential side effects to plugging? Is it really a "safer" way to use E?

I am curious about the effectiveness of ketamine for therapy and recovery of drug use in young people/teenager in depression and success rate.

Hi, where can I test my molly on or near campus?

Me and my friends are users of X. We know that it's illegal and not good for you, but it's only a once in a while thing. My question is that I know there are different types of X pills that you can take. We have been getting motorolas and I know a friend told me that mitsubishis are really bad to take. I was wondering the differences between the pills and the differences between triple and double stacked pills......

I heard that the first reaction you have to taking ecstasy is to become violently ill, after which the party can continue. This sounds like an urban legend to me. Could you clarify please?