I have heard that people can become trapped in their own world of hallucinations permanently from taking 'shrooms, acid, or other hallucinogens and have to live in a mental health facility because they are so out of touch with reality. I'm wondering is this true? And if so what is this medical condition called? I've heard of Hppd, but what I have read about it, it doesn't sound exactly the same. I'm also curious what the likelihood of this happening would be and if it is dependent on the use of many drugs, dosage, or the user's mental state or other preexisting health conditions that could affect this. I'm really hoping you can answer this question because I haven't found any reliable sources about this topic.

Thanks so much!

Is it true that women can apply testosterone cream to their vaginal area to increase sex drive?

1) I have two friends who I think are drinking too much. I don't know what to do. They are very defensive should anyone say anything to them about their excessive habit, and a lot of our friends are giving up on them. This has become a daily thing and their schoolwork and friendships are all suffering. They are both 21; one recently broke up with his girlfriend of several years and the other has been single for a while and he hates it. I know that has a lot to do with it. Please suggest some non-intrusive ways to help them. I'm really at a loss.

2) Last year, I became very good friends with a guy on my floor. He was a little out of the ordinary in the way he dressed, as well as in some of his opinions and habits. I had the feeling that he did drink more than he should, and he also did pot. I did not worry too much about it because it appeared to be more of a lifestyle choice than an addiction, and it did not cause him major troubles.

Unfortunately, he started to have academic problems. He did not do his work, missed classes, and eventually exams as well. I still did not relate these things to his alcohol and drug habits, and I hoped that once he got over the adjustment everyone needed to make in freshman year, he would be fine. Well, he wasn't. He did not come back to school this fall, and when I called him, I learned that he had gone through a lot that summer. He was diagnosed with depression and a cocaine addiction, put on Prozac, and sent to therapy. At that point, I thought that he was on the right track because he was also going to get a job and planning to take classes at a nearby college.

However, when he came to visit me a month later, he had already had two beers before he even came here and got more and more drunk as the evening progressed. I would not let him drive home, but he ignored my warnings and left anyway. I was very disturbed because a friend of his had just been in a drunk driving accident. I was very mad at him, told him clearly that I will always be his friend but prefer not to talk to him or see him if he showed up drunk again. He did not call for a while and neither did I. When he called me yesterday and I told him that I thought he should do something about his alcohol problem, he kept repeating his excuses, that he drinks because he is Irish, that he doesn't care if he dies early as long as he had fun in life, etc. On the other hand, he can't find a job and seems to be very depressed. I want to help him, but I don't know how. Any ideas?

My new job requires me to travel by airplane quite a bit. While flying, I sometimes have a cocktail or two, and most of the time, I am really loopy by the time we land. Some colleagues of mine have told me that one drink in the air is the equivalent of two drinks on the ground. How is this possible?

1) What are the long-term and short-term effects of abusing NyQuil? I've heard it's very dangerous to use it recreationally, but I'm not sure what's dangerous about it. I've heard you can even die from abusing it.

2) I have recently just finished my first year in college and on a few occasions, a couple of friends and I had decided to drink massive amounts of Robitussin DM (dextromethorphan, I believe). It was fun, but the day after I felt like I was hit by a car! They call it robo trippin'. I have no intentions on doing this again; however, I was wondering if there were any long-term effects of it.