Is mixing uppers and downers a bad idea?

Recently, many of my friends have been doing methamphetamines. Often when they start to come down, want to come down, want to "level" out their high, etc. they take Xanax!!! Now I know Xanax is an anti-anxiety drug, and meth speeds your heart up. So can mixing the two ("reds" with "blues") be especially bad? I keep trying to tell them that it doesn't sound like a good idea...but they know that I hate pills so they DON'T listen. "They know better!" But I haven't been able to find any info specific to my question in other places. CAN YOU HELP?


Will past experimentation with drugs lead to permanent brain damage?

I have a history of "experimentation" (infrequent or occasional use of ecstasy, 'shrooms, and other drugs — mostly prescription pills). I am completely sober now, but am worried about long-term damage to my brain. I used drugs infrequently (no more than three to five times for each substance), but drank regularly. How worried should I be? Is there anything I can do to combat long-term effects?


How can I take care of my nails if I’m a chronic nail biter?

I am curious as to whether the nail bed regenerates or not. I used to bite my nails, and slowly I've bitten off some of the nail bed as well, on all ten fingers. It has been two years, and the nail bed does not seem to grow back, and my nails grow according to the new shape of the nail bed. It makes my hands look somewhat ugly, to be honest.

Any suggestions would be appreciated.


How do I manage unwanted hair growth as someone assigned female at birth?

1) I have a really embarrassing problem... I have hair on my chest and I am a woman! It's not really thick, but it's very noticeable, and I hate it! Is this a hormone problem or is it normal? Please help, 'cause to me, it's gross and I will do anything to get rid of it. I have been shaving it, but it just grows back within a few days or so. Please help!

2) I am a 24 year old female and for the past few years I have had facial hair. I tend to get it on my chin and the side of my face. It is usually light but you can feel it, and I will never let my boyfriend touch my face unless I have just shaved it.

I don't want to go for laser treatment, is their anything else you could suggest? I feel disgusting and very unwomanly.


Does a shampoo additive (sodium lauryl sulfate) cause cancer?

I was wondering about the chemical sodium laureth sulfate. I have received several forwarded e-mails about this causing cancer by a lawyer looking into the matter. This chemical was said to be in many shampoos to create a nice lather, but it's actually a garage cleaner and is a cheap substance for the manufacturer, and in the past, only 1 in 2000 would get cancer from this, and now it's about 1 in 10. I was just curious if it really causes cancer, or is it just a prank? And if it really does cause cancer, what kind of cancer is it? Thank you. I would appreciate an honest answer.


Is it okay to drink alcohol while on Zoloft?

I just started taking Zoloft today. I am going on vacation next week and am wondering if it is safe to drink while on this medication. I can't seem to get a straight answer from anyone. I'm not talking about drinking to oblivion; I'm talking about having a couple of drinks by the campfire. Is this okay?