I'm curious about drugs — in particular what happens when you chemically combine methamphetamine and PCP and how it might affect the body. Some places online say they're the same thing, but I'm not so sure.

On "big nights out" (about once a month) friends of mine "plug" ecstasy tablets — by which I mean they each stick one up their butt instead of swallowing.

They claim that is a "safer" way to ingest E because it bypasses the liver and goes right into the bloodstream. They also claim the effects are heightened.

I have been tempted to try this method as they swear by it, but thought I'd get your opinion first — are there any potential side effects to plugging? Is it really a "safer" way to use E?

Hi, where can I test my molly on or near campus?

Is lsd safe to use while on an SSRI.

Me and my friends are users of X. We know that it's illegal and not good for you, but it's only a once in a while thing. My question is that I know there are different types of X pills that you can take. We have been getting motorolas and I know a friend told me that mitsubishis are really bad to take. I was wondering the differences between the pills and the differences between triple and double stacked pills......

I heard that the first reaction you have to taking ecstasy is to become violently ill, after which the party can continue. This sounds like an urban legend to me. Could you clarify please?

I have two friends who were recently diagnosed with depression. They were both prescribed Prozac by their respective doctors. Both of them are heavy marijuana users and both failed to mention that to their doctors. One has been on Prozac for two months and the other for six weeks. I have noticed that their behavior has become strange: mood swings, paranoia, oversleeping, fatigue. They continue taking their Prozac (20 mg a day) and continue smoking pot. I am afraid that there might be some negative interaction between the substances, one being an antidepressant and the other a depressant. Can you provide some insight?

Recently, my boyfriend began injecting cocaine. I've noticed that he and his friends share their needles, but "clean" them first with bleach and water. Is this a valid way to avoid contamination?

My friend recently smoked some pot laced with cocaine. First of all, is this possible? Whatever the case may be, he seems to be infatuated with the idea of trying straight coke. I've heard that trying coke for the first time is quite dangerous, true? Also, what are the effects of the high? And how detrimental is coke in general?

Could you possibly tell me the interactive effects of Zoloft (the anti-depressant) and MDMA (Ecstasy)?