I have been taking between 5 and 10 mgs of methadone daily. I cannot seem to stop. Every time I try, I get very, very depressed and experience abdominal pain, chills, hot flashes, and sleeplessness. The depression and tremendous anxiety are intolerable and I end up taking more to avoid it. Question: Am I harming my body and/or mind with this stuff? How can I get off without the horrible feelings?

My friend and I snorted a 10 bag each of heroin. Our heads began to feel heavy after ten minutes. Soon we entered into a dream world in which we hallucinated heavily. We talked to people who did not exist and we were very confused. I could not remember anything about who I was. I only remember certain parts of the four-hour trip that followed but I felt like I was on mushrooms for about two days. We could not read for that amount of time (nothing was in focus). What do you think we took? PCP? Bad synthetic heroin?

I'm thinking about trying heroin. However, this prospect makes me nervous because of all the media reports of people becoming so quickly addicted to it, wasting away, and even dying from overdoses. Any advice?

I know that it is extremely dangerous to mix viagra (or other ED drugs) and poppers (amyl nitrate), and that one should wait for 24 hours after using viagra (to let it get out of your system) before using poppers. My question is what is the waiting period after using poppers before it is safe to use viagra? In other words, how long before the physiological effects of poppers wear off?

A couple of questions for you: what are the long-term side effects of one abusing prescription painkillers, such as Vicodin? What advice can you give to someone who has gotten off of them to help them stay off???

I have been shooting cocaine steadily for almost two months now and want to know what the difference between the physical and emotional addiction is. I am not sure if I have been experiencing withdrawals, but I feel sick a lot lately. I know shooting heroin has made me sick before. Can cocaine eventually make you dope sick as well?

I just started taking Zoloft today. I am going on vacation next week and am wondering if it is safe to drink while on this medication. I can't seem to get a straight answer from anyone. I'm not talking about drinking to oblivion; I'm talking about having a couple of drinks by the campfire. Is this okay?