On "big nights out" (about once a month) friends of mine "plug" ecstasy tablets — by which I mean they each stick one up their butt instead of swallowing.

They claim that is a "safer" way to ingest E because it bypasses the liver and goes right into the bloodstream. They also claim the effects are heightened.

I have been tempted to try this method as they swear by it, but thought I'd get your opinion first — are there any potential side effects to plugging? Is it really a "safer" way to use E?

I am curious about the effectiveness of ketamine for therapy and recovery of drug use in young people/teenager in depression and success rate.

Hi, where can I test my molly on or near campus?

Is lsd safe to use while on an SSRI.

Me and my friends are users of X. We know that it's illegal and not good for you, but it's only a once in a while thing. My question is that I know there are different types of X pills that you can take. We have been getting motorolas and I know a friend told me that mitsubishis are really bad to take. I was wondering the differences between the pills and the differences between triple and double stacked pills......

I heard that the first reaction you have to taking ecstasy is to become violently ill, after which the party can continue. This sounds like an urban legend to me. Could you clarify please?

I am a 23 year old female who enjoys a few glasses of wine but, in my opinion, doesn't drink more than the average college student. A few weeks ago, I had quite a bit to drink and haven't felt the same since. I am dizzy, forgetful, confused and my liver is very tender to the touch. I have continued to have a few glasses of wine a couple nights out of the week and it seems to be the only thing that gets me back to feeling "normal." Is this a normal way to feel or should I be concerned?