How do marijuana and Prozac interact?

I have two friends who were recently diagnosed with depression. They were both prescribed Prozac by their respective doctors. Both of them are heavy marijuana users and both failed to mention that to their doctors. One has been on Prozac for two months and the other for six weeks. I have noticed that their behavior has become strange: mood swings, paranoia, oversleeping, fatigue. They continue taking their Prozac (20 mg a day) and continue smoking pot. I am afraid that there might be some negative interaction between the substances, one being an antidepressant and the other a depressant. Can you provide some insight?


Who can I talk to about loss?

My father just died. I'm really depressed. I'm not looking for sympathy, so I haven't told any of my friends. I'm not on good terms with my family and that has made the situation all the more difficult. I feel like I need somebody to talk to, but I'm afraid to approach my friends. I know in situations like this people over-compensate by smothering the person with sympathy and attention. What I need is the exact opposite. I need to work this out on my own. Maybe someone that will be there when I want them to be. I'm not looking for the number of a hotline where I will just end up talking to a stranger. Nor do I want to talk to the counselors or any other strangers. You're the first person that I've said anything to about this. Who can I talk to about this?


What are the effects of recreational nitrous oxide use?

1) I am wondering about the direct effects nitrous oxide has on the brain, and if it is a fallacy that it kills brain cells.

2) What are the health dangers of inhaling nitrous oxide? I have heard people say that it "kills brain cells," but no one seems to know how, to what extent, and what the resulting effects are. Since nitrous oxide is commonly administered as anesthesia, is there a safe way to consume it for recreational use? If the user controls her oxygen intake, do the harmful effects (if any) still occur?


What should I do about friend's escalating drug use?

I have a friend at school who quit smoking last year in January, and went back to it in October. I have no idea why, and he also started doing other drugs, such as smoking blunts, doing ecstasy, and taking steroids. The drug that I am worried about him doing the most is ecstasy, because it's a dangerous drug. Also, he is always talking about doing drugs. How can I help him? I still want him to be my friend. Please help. This is serious.