My friend recently smoked some pot laced with cocaine. First of all, is this possible? Whatever the case may be, he seems to be infatuated with the idea of trying straight coke. I've heard that trying coke for the first time is quite dangerous, true? Also, what are the effects of the high? And how detrimental is coke in general?

I was really drunk and don't remember the night clearly, but I think I may have had sex. Now I don't know if I could be pregnant or not. I had never had sex before this. Help me please!

Could you possibly tell me the interactive effects of Zoloft (the anti-depressant) and MDMA (Ecstasy)?

1) I am wondering about the direct effects nitrous oxide has on the brain, and if it is a fallacy that it kills brain cells.

2) What are the health dangers of inhaling nitrous oxide? I have heard people say that it "kills brain cells," but no one seems to know how, to what extent, and what the resulting effects are. Since nitrous oxide is commonly administered as anesthesia, is there a safe way to consume it for recreational use? If the user controls her oxygen intake, do the harmful effects (if any) still occur?

I have a friend at school who quit smoking last year in January, and went back to it in October. I have no idea why, and he also started doing other drugs, such as smoking blunts, doing ecstasy, and taking steroids. The drug that I am worried about him doing the most is ecstasy, because it's a dangerous drug. Also, he is always talking about doing drugs. How can I help him? I still want him to be my friend. Please help. This is serious.

I recently drank one shot of absinth(e) mixed with water at a party. I read up on it online and opinions differ vastly as to the potential for negative side effects. At this point my imagination has me suffering every possible one.

I would like to know the true possible effects and if one drink could realistically cause them. If it helps, the brand I had contained 100mg of thujone and it was Czech and I'm told they use an extract which is worse than using straight wormwood.

I hope you can help because I'm a little freaked out, the guy who gave it to me drank it extensively and recently committed suicide and I'm convinced the cause in part was the Absinthe.

I have smoked marijuana on and off for about a year, not ever more than about once every other week. The last two times I smoked, I experienced uncontrollable tremors in my leg. It wasn't painful like a muscle spasm, but it was uncomfortable and unsettling. Was this merely nervousness (this was the first time I had people "over" at my own suite to smoke and I was a little worried that my roommates would be angry)? Or, could this be a side effect of the drug?

Lately, I have been doing a drug called Special K. I know it is a sedative/tranquilizer (what's the difference?), but very little about side effects, etc. Also, can you go over similar information about the drug X?